Subcutaneous allergen immunotherapy has been demonstrated to be a safe and effective treatment for individuals allergic to a common fungus.
Genetic Variants of Receptor Detecting Inflammation and Tissue Damage May Increase Susceptibility for Depression
Genetic variants of an innate immune receptor that detects inflammation and tissue damage have been associated with HADS depression severity scores by a group of Hungarian researchers.
Alteration of White Blood Cell Population by Chronic Inflammation May Underlie Long-Term Gluten Sensitivity of Celiac Disease Patients
Chronic gluten-associated inflammation has recently been demonstrated to alter the profile of intraepithelial resident memory T cells, a white blood cell subset capable of surviving independently within the intestinal tissue for extended periods of time, to engender the long-term gluten sensitivity characteristic of Celiac Disease.
Lymph Vessel Network Important for Combatting Rheumatic Diseases, Potential Role for Alternative Medicine
New research and treatments for Rheumatic Diseases may focus on the lymphatic system, a network of fluid-carrying vessels distributed throughout the body.
A therapy for steroid-refractory and/or resistant Graft-versus-Host-Disease may function by favorably altering a population of circulating white blood cells.
Possible Combination Treatment for Patients with Cancers not Responsive to Immune Checkpoint Inhibitors
The use of a drug stimulating an innate immune receptor could render immune checkpoint inhibitors functional in patients with otherwise unresponsive cancers.
The expression level of the protein Interleukin-21 in circulating immune cells may predict kidney transplant rejection prior to surgery.
Possible Combination Therapy for Sensitized Kidney Transplant Recipients Harnesses Existing Cancer Drug
Combining an existing cancer drug with costimulation blockade has shown promise in non-human primates for enabling transplantation of sensitized recipients.
CAR T Cells Show Efficacy for the Treatment of Relapsed and/or Refractory Aggressive Large B Cell Lymphoma
CAR T cells continue to show efficacy for the treatment of relapsed and/or refractory large B cell lymphoma.